Telemedicine & Digital Health

Biography

Biography: Olena M. Klyuchko

Abstract

Presented investigations started at research centre of Caucasus Mountains – Elbrus Medical and Biological Station (EMBS) of the National Academy of Sciences of Ukraine [1] at m.Elbrus slopes (2100 m a.s.l.), v.Terskol (now – territory of Russia). Research works here were organized by Academician Sirotinin MM many years ago [1], his outstanding scientific "hypoxic" school reached the heights of pathophysiological science, being the source of many theories, ideas and practically used inventions.

Investigations of this scientific school are known, at EMBS were united efforts of many research groups from different countries, as well as Ukrainian researchers. Due to their achievements Kyiv was called “the capital of hypoxia studies” (Academician Chernigovsky VM, 1980-th) [1]. Studies of organisms reliability problems in extreme conditions stimulated the need to involve telemetric methods, as well as nowel technical and mathematical ones [1]. In the late 1970-th Ukrainian researchers there used the method to monitor electrocardiograms (ECG) and oxygen saturation  in organisms of climbers to Elbrus Mountain (5642 m a.s.l.), from the distance up to 10 km with portable radio. Along with traditional experimental research methods in fields of extreme, ecological, aerospace, sports physiology there were developed mathematical models of main functional systems of organism: models of functional respiratory system, adaptation to hypoxia, estimation of hypoxia development at coronary heart disease, cerebral ischemia, etc. (OnopchukYuM, Beloshitsky PV, Klyuchko OM, 2008). This made it possible to predict the state of organism in extreme situations; use the received information for forecasting, effective treatment, training, improvement of sports results, increase of organism resistance [1]. The conducted fundamental researches have allowed: for the first time in the world practice to open new highly effective direction - hypoxytherapy for treatment, prevention, rehabilitation, increase of resistance and working capacity; substantiate the concepts of stepwise adaptation to hypoxibaria, of organism oxygen regimes, changes in reactivity and resistance in phylogeny and ontogenesis; introduce such concepts as reliability of organism functioning (Beloshitsky PV, 1989), bioinformation (Beloshitsky PV, Beloshitsky SP, 2002), offer to define information diseases and information methods of treatment (Beloshitsky PV, Beloshitsky SP, Klyuchko OM, 2002, 2003). These works permitted to transform the science about hypoxia from experimental-descriptive into numerical one with possibility of future digitalization [1, 2]; this was a new breakthrough in the system of knowledge about human in those years.

Today the technical part of these works is continued in National Aviation University (NAU), Kyiv (Ukraine), where the information system for large-scale monitoring of environment “EcoIS” with telecommunication possibilities was developed [2-5] together with included automated work places [6], expert system [7], and etc. (Klyuchko OM, 2014-2021) This new specialized computer-based information system permits to monitor the changes in organisms as result of chemical environmental pollution in wide time ranges (from 0 to few years after the influence) using modern information and telecommunication technologies, on the base of novel databases and detector groups [3-5]. Together with this, the development in NAU means for distant education, means of telecommunications permits to use and demonstrate digitalized educative materials for all courses distantly that is especially important during Covid-19 pandemia. Distant means of education and telecommunication possibilities developed in NAU permit to demonstrate students the results obtained previously at EMBS as files of different formats, including educative movies, chronicles, obtained experimental data, and etc; as well as results of “EcoIS” system development together with its constituent elements and used methods